FACTOR IX CONCENTRATES

CLINICAL PRACTICE GUIDELINES
Hemophilia and von Willebrand’s Disease: 2. Management
(Edition 2, Update 2 [1999-07-07])

Factor IX concentrates (hemophilia B)
The following types of concentrate are available:
• Recombinant factor IX (rFIX) concentrate. The clotting factor is produced in cultured hamster cells in the absence of human proteins, and formulated without the use of human albumin as a stabilizer.
• High-purity plasma-derived Factor IX concentrates containing a negligible amount of other vitamin K-dependent clotting factors (i.e., Factors II, VII and X).
• Prothrombin-complex concentrate. This product has an intermediate degree of purity and contains significant amount of other vitamin K-dependent clotting factors.

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